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Publications in 2022

publications in 2022

 

43  journal articles, one book chapter, impact factor: 188

  Papers IF
1. Abdelghafour MM, Orbán Á, Deák Á, Lamch Ł, Frank É, Nagy R, Ziegenheim S, Sipos P, Farkas E, Bari F, Janovák L.  Biocompatible poly(ethylene succinate) polyester with molecular weight dependent drug release properties.  Int J Pharm. 2022 Apr 25;618:121653. 3,061
2. Gargyan I, Dozsai D, Csonka I, Rarosi F, Bodzay T, Csonka A.  Bisphosphonate therapy associated with bilateral atypical femoral fracture and delayed union.  Joint Dis Relat Surg. 2022;33(1):24–32. 1,549
3. Kis M, Smart JL, Maróti P.  Capacity and kinetics of light-induced cytochrome oxidation in intact cells of photosynthetic bacteria.  Sci Rep. 2022;12(1):14298. 4,997
4. Etlinger P, Barroso C, Miranda A, Moreira Pinto J, Lamas-Pinheiro R, Ferreira H, Leão P, Kovács T, Juhász L, Sasi Szabó L, Farkas A, Vajda P, Kálmán A, Géczi T, Simonka Z, Cserni T, Nógrády M, Fodor GH, Szabó A, Correia-Pinto J.  Characterization of technical skill progress in a standardized rabbit model for training in laparoscopic duodenal atresia repair.  Surg Endosc. 2022 Apr;36(4):2456–65. 3,453
5. Paszt A, Ottlakan A, Abraham S, Simonka Z, Vas M, Maraz A, Szepes Z, Tiszlavicz L, Nyari T, Olah J, Lazar G.  Clinical benefits of oral capecitabine over intravenous 5-fluorouracyl regimen in case of neoadjuvant chemoradiotherapy followed by surgery for locally advanced rectal cancer.  Pathol Oncol Res. 2022;28:1610722. 2,874
6. Kondoros BA, Berkesi O, Toth Z, Aigner Z, Ambrus R, Csoka I.  Cyclodextrin Complexation of Fenofibrate by Co-Grinding Method and Monitoring the Process Using Complementary Analytical Tools.  Pharmaceutics. 2022 Jul;14(7):1329. 6,525
7. Jávor P, Rárosi F, Horváth T, Török L, Varga E, Hartmann P.  Detection of exhaled methane levels for monitoring trauma-related haemorrhage following blunt trauma: study protocol for a prospective observational study.  BMJ Open. 2022 Jul 6;12(7):e057872. 3,007
8. Lohner T, Nemeth A, Zolnai Z, Kalas B, Romanenko A, Khanh NQ, Szilagyi E, Kotai E, Agocs E, Toth Z, Budai J, Petrik P, Fried M, Barsony I, Gyulai J.  Disorder and cavity evolution in single-crystalline Ge during implantation of Sb ions monitored in-situ by spectroscopic ellipsometry.  Mater Sci Semicond Process. 2022 0;152:107062. 4,644
9. Peták F, Balogh ÁL, Hankovszky P, Fodor GH, Tolnai J, Südy R, Kovács BN, Molnár A, Babik B.  Dopamine Reverses Lung Function Deterioration After Cardiopulmonary Bypass Without Affecting Gas Exchange.  J Cardiothorac Vasc Anesth. 2022 Apr;36(4):1047–55. 2,894
10. Institóris L, Hidvégi E, Kovács K, Jámbor Á, Dobos A, Rárosi F, Süvegh G, Varga T, Kereszty ÉM.  Drug consumption of suspected drug-influenced drivers in Hungary (2016-2018).  Forensic Sci Int. 2022 Jul;336:111325. 2,676
11. Török L, Jávor P, Török K, Rárosi F, Hartmann P.  Early Return to Play After Anterior Cruciate Ligament Reconstruction: Is It Worth the Risk?  Ann Rehabil Med. 2022 Apr;46(2):97–107. 0,63
12. Dos Santos Rocha A, Diaper J, Balogh AL, Marti C, Grosgurin O, Habre W, Peták F, Südy R.  Effect of body position on the redistribution of regional lung aeration during invasive and non-invasive ventilation of COVID-19 patients.  Sci Rep. 2022 Jun 30;12(1):11085. 4,997
13. Maroti P, Kis M.  Environmental protection via biomonitoring lead exposure by photosynthetic purple bacteria.  Plant Physiol Rep [Internet]. [cited 2022 Dec 30]; Available from: https://www.webofscience.com/wos/woscc/summary/fab15c8d-125a-4e2a-9188-a22e02f7a860-67f3c5ef/relevance/1 0
14. Spekker E, Bohár Z, Fejes-Szabó A, Szűcs M, Vécsei L, Párdutz Á.  Estradiol Treatment Enhances Behavioral and Molecular Changes Induced by Repetitive Trigeminal Activation in a Rat Model of Migraine.  Biomedicines. 2022;10(12):3175. 4,757
15. Schranc Á, Fodor GH, Südy R, Tolnai J, Babik B, Peták F.  Exaggerated Ventilator-Induced Lung Injury in an Animal Model of Type 2 Diabetes Mellitus: A Randomized Experimental Study.  Front Physiol. 2022;13:889032. 4,755
16. Peták F, Fodor GH, Schranc Á, Südy R, Balogh ÁL, Babik B, Dos Santos Rocha A, Bayat S, Bizzotto D, Dellacà RL, Habre W.  Expiratory high-frequency percussive ventilation: a novel concept for improving gas exchange.  Respir Res. 2022 Oct 15;23(1):283. 7,162
17. Schranc Á, Balogh ÁL, Diaper J, Südy R, Peták F, Habre W, Albu G.  Flow-controlled ventilation maintains gas exchange and lung aeration in a pediatric model of healthy and injured lungs: A randomized cross-over experimental study.  Front Pediatr. 2022;10:1005135. 3,569
18. Kallab R, Sudy R, Dos Santos Rocha A, Diaper J, Petak F, Keli Barcelos G, Habre W.  Invasive and non-invasive assessment of macro- and micro-circulatory effects of vasopressors during sevoflurane anesthesia in a pediatric experimental model: A randomized trial.  Paediatr Anaesth. 2022 Oct;32(10):1129–37. 0,983
19. Sipka G, Nagy L, Magyar M, Akhtar P, Shen J-R, Holzwarth AR, Lambrev PH, Garab G.  Light-induced reversible reorganizations in closed Type II reaction centre complexes: physiological roles and physical mechanisms.  Open Biol. 2022;12(12):220297. 7
20. Laurent D, Riek J, Sinclair CDJ, Houston P, Roubenoff R, Papanicolaou DA, Nagy A, Pieper S, Yousry TA, Hanna MG, Thornton JS, Machado PM.  Longitudinal Changes in MRI Muscle Morphometry and Composition in People With Inclusion Body Myositis.  Neurology. 2022 0;99(9):E865–76. 12,258
21. Schranc Á, Fodor GH, Südy R, Ballók B, Kulcsár R, Tolnai J, Babik B, Peták F.  Lung and chest wall mechanical properties in metformin-treated and untreated models of type 2 diabetes.  J Appl Physiol (1985). 2022 May 1;132(5):1115–24. 3,881
22. Menyhárt Á, Frank R, Farkas AE, Süle Z, Varga VÉ, Nyúl-Tóth Á, Meiller A, Ivánkovits-Kiss O, Lemale CL, Szabó Í, Tóth R, Zölei-Szénási D, Woitzik J, Marinesco S, Krizbai IA, Bari F, Dreier JP, Farkas E.  Malignant astrocyte swelling and impaired glutamate clearance drive the expansion of injurious spreading depolarization foci.  J Cereb Blood Flow Metab. 2022 Apr;42(4):584–99. 6,597
23. Császár E, Lénárt N, Cserép C, Környei Z, Fekete R, Pósfai B, Balázsfi D, Hangya B, Schwarcz AD, Szabadits E, Szöllősi D, Szigeti K, Máthé D, West BL, Sviatkó K, Brás AR, Mariani J-C, Kliewer A, Lenkei Z, Hricisák L, Benyó Z, Baranyi M, Sperlágh B, Menyhárt Á, Farkas E, Dénes Á.  Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions.  J Exp Med. 2022 Mar 7;219(3):e20211071. 17,579
24. Lemale CL, Lückl J, Horst V, Reiffurth C, Major S, Hecht N, Woitzik J, Dreier JP.  Migraine Aura, Transient Ischemic Attacks, Stroke, and Dying of the Brain Share the Same Key Pathophysiological Process in Neurons Driven by Gibbs-Donnan Forces, Namely Spreading Depolarization.  Front Cell Neurosci. 2022;16:837650. 6,147
25. Sarrai AE, Belaissa Y, Kirdi R, Hanini S, Szabo T, Nagy L.  Modeling and optimization of Tylosin adsorption using dehydrated wheat bran: adsorption behaviors, kinetic and thermodynamic studies.  React Kinet Mech Catal. 2022 0;135(4):1905–28. 1,843
26. Fabo C, Oszlanyi A, Lantos J, Rarosi F, Horvath T, Barta Z, Nemeth T, Szabo Z.  Non-intubated Thoracoscopic Surgery-Tips and Tricks From Anesthesiological Aspects: A Mini Review.  Front Surg. 2021;8:818456. 2,568
27. Cserni B, Bori R, Csörgő E, Oláh-Németh O, Pancsa T, Sejben A, Sejben I, Vörös A, Zombori T, Nyári T, Cserni G.  ONEST (Observers Needed to Evaluate Subjective Tests) suggests four or more observers for a reliable assessment of the consistency of histological grading of invasive breast carcinoma: A reproducibility study with a retrospective view on previous studies.  Pathol Res Pract. 2022;229:153718. 3,309
28. Luckl J, Baker W, Boda K, Emri M, Yodh AG, Greenberg JH.  Oxyhemoglobin and Cerebral Blood Flow Transients Detect Infarction in Rat Focal Brain Ischemia.  Neuroscience. 2022;509:132–44. 3,708
29. Anna V, Bernadett B, Andrea O, Mónika S, Attila N, ifj LG, István B, Péter K, Tamás V, Csaba L.  Peripheral sensory and cardiovascular autonomic dysfunction in kidney transplant patients.  DIABETES STOFFWECHSEL UND HERZ. 2022;31(3):42–50. 0,18
30. Dos Santos Rocha A, Peták F, Carvalho T, Habre W, Balogh AL.  Physiologically variable ventilation prevents lung function deterioration in a model of pulmonary fibrosis.  J Appl Physiol (1985). 2022 Apr 1;132(4):915–24. 3,881
31. Hajdu K, Balderas-Valadez RF, Carlino A, Agarwal V, Nagy L.  Porous silicon pillar structures/photosynthetic reaction centre protein hybrid for bioelectronic applications.  Photochem Photobiol Sci. 2022;21(1):13–22. 4,328
32. Cserni G, Ambrózay É, Serényi P, Bori R, Sejben I, Csörgő E, Serfőző O, Lóránd K, Venczel L, Maráz R, Sinkó M, Szeleczki N, Nyári T, Zombori T.  Preoperative axillary nodal staging of invasive lobular breast cancer with ultrasound guided fine needle aspiration in patients with suspicious ultrasound findings versus aspiration in all patients - A retrospective single institutional analysis.  Eur J Surg Oncol. 2022 Apr;48(4):742–7. 3,184
33. Pálinkás ED, Re F, Peteiro J, Tesic M, Pálinkás A, Torres MAR, Dikic AD, Beleslin B, Van De Heyning CM, D’Alfonso MG, Mori F, Ciampi Q, de Castro Silva Pretto JL, Simova I, Nagy V, Boda K, Sepp R, Olivotto I, Pellikka PA, Picano E.  Pulmonary congestion during Exercise stress Echocardiography in Hypertrophic Cardiomyopathy.  Int J Cardiovasc Imaging. 2022;38(12):2593–604. 2,316
34. Peták F, Kovács BN, Agócs S, Virág K, Nyári T, Molnár A, Südy R, Lengyel C, Babik B.  Seasonal changes in proportion of cardiac surgeries associated with diabetes, smoking and elderly age.  PLoS One. 2022;17(9):e0274105. 3,752
35. Boga B, Székely I, Focșan M, Baia M, Szabó T, Nagy L, Pap Z.  Sensor surface via inspiration from Nature: The specific case of electron trapping in TiO2/WO3(∙0.33H2O) and reaction center/WO3(∙0.33H2O) systems.  Applied Surface Science. 2022;572. 7,392
36. Balogh AL, Sudy R, Petak F, Habre W, Dos Santos Rocha A.  Sevoflurane and Hypercapnia Blunt the Physiological Variability of Spontaneous Breathing: A Comparative Interventional Study.  Front Physiol. 2022;13:871070. 4,755
37. Török N, Maszlag-Török R, Molnár K, Szolnoki Z, Somogyvári F, Boda K, Tanaka M, Klivényi P, Vécsei L.  Single Nucleotide Polymorphisms of Indoleamine 2,3-Dioxygenase 1 Influenced the Age Onset of Parkinson’s Disease.  Front Biosci (Landmark Ed). 2022 Sep 27;27(9):265. 3,115
38. Dreier JP, Winkler MKL, Major S, Horst V, Lublinsky S, Kola V, Lemale CL, Kang E-J, Maslarova A, Salur I, Lückl J, Platz J, Jorks D, Oliveira-Ferreira AI, Schoknecht K, Reiffurth C, Milakara D, Wiesenthal D, Hecht N, Dengler NF, Liotta A, Wolf S, Kowoll CM, Schulte AP, Santos E, Güresir E, Unterberg AW, Sarrafzadeh A, Sakowitz OW, Vatter H, Reiner M, Brinker G, Dohmen C, Shelef I, Bohner G, Scheel M, Vajkoczy P, Hartings JA, Friedman A, Martus P, Woitzik J.  Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study.  Brain. 2022 May 24;145(4):1264–84. 15,255
39. Lantos T, Nyári TA.  The impact of the COVID-19 pandemic on suicide rates in Hungary: an interrupted time-series analysis.  BMC Psychiatry. 2022;22(1):775. 4,144
40. Menyhárt Á, Varga DP, M Tóth O, Makra P, Bari F, Farkas E.  Transient Hypoperfusion to Ischemic/Anoxic Spreading Depolarization is Related to Autoregulatory Failure in the Rat Cerebral Cortex.  Neurocrit Care. 2022 Jun;37(Suppl 1):112–22. 3,532
41. Molnár T, Domján A, Szűcs M, Surányi A, Bódis J.  Utilizing Synergism between the Transverse Abdominal and Pelvic Floor Muscles at Different Postures in Nulliparous Women: A Randomized Case-Control Study.  Urol Int. 2022;106(3):274–81. 1,934
42. Aranyné Molnár T, Presznerné Domján A, Szűcs M, Surányi A, József B.  Utilising Synergism Between the Transverse Abdominal and Pelvic Floor Muscles at Different Postures in Nulliparous Women: a Randomized Case Control Study.  BMC WOMENS HEALTH [Internet]. 2021 2,809
43. L. Nagy, M. Magyar (2022) No Alternatives to Photosynthesis: From Molecules to Nanostructures In: Jeschke, P., & Starikov, E.B. (Eds.). Agricultural Biocatalysis: Theoretical Studies and Photosynthesis Aspects (1st ed.). Jenny Stanford Publishing.  
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Medical Physics and Statistics
(examination statistics)

Academic year 2020-2021, 1st semester

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Medical physics 1.
2019-2020. 1st semester

obligatory course

COURSE DATA

Course title: Medical physics 1

Credits: 2

Course code: AOK-KUA508

Assessment: end-semester examination

Lecture: 1 period/week

  • Thursdays, 13:00–13:45 in the Ivánovics György lecture room (Big Education Centre)

Seminar: 1 period/week

AIM OF THE COURSE

In accordance with the widespread involvement of physical principles and methods in almost all areas of medical sciences, this compulsory course offers an introduction to applications of physics in medicine and clinical research.

The physics syllabus is designed to facilitate the understanding of certain phenomena in the physiology of the human body (kinetics of the body, muscle function, circulation, respiration, sensing, transport phenomena) by studying the underlying physical principles.

The 2 hours/week physics lecture is accompanied by 2 hours/fortnight seminars. These seminars are dedicated to discussing lecture material and clarifying the questions that may arise.

There is a five-grade written examination covering the material of lectures, seminars and the relevant chapters of the obligatory textbooks at the end of both semesters. Assessment is based on the material covered in the lectures and seminars and on the relevant chapters of the obligatory reading.

REQUIREMENTS FOR THE SUCCESSFUL COMPLETION OF THE COURSE

Attendance of the lectures is strongly recommended; downloading the lecture slides cannot substitute for the participation at the lecture. We perform attendance checks regularly.

To complete this course successfully, one needs to have a certain grasp of the fundamentals of physics. We shall check students’ knowledge in the first two weeks of the semester and offer the course Fundamentals of medical physics to those whose scores are lower in order to help them brush up their physics skills.

The lectures are complemented by biweekly seminars whose aim is to help students reach a deeper understanding of the lecture material. Attending seminars is obligatory and active participation is expected. In duly justified cases (disruptive behaviour, blatant passivity or lack of preparedness) the seminar instructor has the right to refuse the student’s further participation and register the student as absent.

Students can have no more than two absences with leave from the seminars. Seminar absences are to be made up for according to the directions of the instructor.

To check if students are prepared, we shall set a short test at the beginning of each seminar. The basis of the seminar tests is the material covered in the previous seminar and the topic list and sample questions available in the CooSpace scene of the course. All seminar tests consist of 3 multiple-choice questions (each worth 1 point) and a single calculation task (worth 2 points).

Only students who have gained the approval of the instructor for their seminar work and achieved at least 20% in the seminar tests (that is, 6 points out of the semester total of 25 points) are eligible to take the examination. If a student fails to meet this, they must take a seminar resit, in which the passing mark is 50%. Failing the resit means they cannot register for an examination and have to repeat the whole course.

The seminar totals will be converted to examination points as follows:

  • 0–5 points: resit must be taken to be able to register for an examination
  • 6–9 points: 1 examination point
  • 10–13 points: 2 examination points
  • 14–17 points: 3 examination points
  • 18–21 points: 4 examination points
  • 22–25 points: 5 examination points

EXAMINATION REQUIREMENTS

The course is worth 2 credits, awarded on the basis of an end-semester examination. Students take a computer-aided multiple-choice test examination at the end of the semester. 25% of test questions cover the material of the seminars, 25% of them consist of fundamental physics questions and 50% of them are medical physics questions. Students have to sign up for the examination through the Neptun system. Examination registrations are finalised automatically 24 hours before the examination. Repetition of examinations is according to the general regulations of the Study and the Examination Requirements of the University. No first examinations are allowed during the resit week of the examination period.

At the examination a maximum of 35 points can be achieved, to which the 5 points obtainable from the seminars are added, making a total of 40 points. Grades of the examination are determined as follows:

  • 0–20 points: failed (1)
  • 21–25 points: passed (2)
  • 26–30 points: accepted (3)
  • 31–35 points: good (4)
  • 36-40 points: excellent (5)

Students who are registered as present at at least 50% of the attendance checks will receive the better mark when lacking just one point: eg, get a passed (2) for 20 points.

SYLLABUS OF THE LECTURES

  1. The significance of physics in life sciences
  2. Mechanics of the human body 1.
  3. Mechanics of the human body 2.
  4. Oscillations and waves in life sciences
  5. Biophysics of the senses: hearing
  6. Principles of fluid mechanics 1.
  7. Principles of fluid mechanics 2.
  8. Physics of biological membranes, diffusion, osmosis.
  9. Thermal interaction between the human body and its environment.
  10. Thermodynamics of transport processes
  11. Medical applications of optics; the optics of vision 1.
  12. Medical applications of optics; the optics of vision 2.
  13. Signals, signal processing, data visualisation.

SYLLABUS OF THE SEMINARS

  1. Fundamentals of mechanics 1.
  2. Fundamentals of mechanics 2.
  3. Oscillations and waves.
  4. Flow of fluids
  5. Thermodynamics.
  6. Optics.

OBLIGATORY TEXTBOOKS

  • S Damjanovich, J Fidy and J Szöllősi (eds): Medical biophysics. Medicina, 2009.

SUGGESTED TEXTBOOKS

  • Paul Davidovits: Physics in biology and medicine. Fourth edition. Academic Press, 2013.
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Medical Physics and Statistics
(examination statistics)

Academic year 2019-2020, 1st semester

 

Academic year 2019-2020, 2st semester

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Fundamentals of medical physics
academic year 2019-2020
1st semester

elective course

COURSE DATA

Course title: Fundamentals of medical physics

Credits: 1

Course code: AOK-KUA441

Assessment: report (five-scale)

Large-group seminar: 16 periods/semester, in blocks

AIM OF THE COURSE

To complete the course Medical physics successfully, students are supposed to be conversant with the secondary-school minimum material in physics, since 25% of the questions will test the general physics background on which the lectures rely.

We shall have a knowledge survey in the first two weeks of the semester, and offer this elective course to students with lower scores to give them the opportunity to bridge their knowledge gap.

REQUIREMENTS FOR THE SUCCESSFUL COMPLETION OF THE COURSE

The classes are held in blocks of 1+3 units per week from week 3 to week 5. Attending these large-group consultations is mandatory for students who have taken this course.

Teaching materials for the course are available on the homepage of our institute (http://www2.szote.u-szeged.hu/dmi/eng/index.php/handouts) and in the respective CooSpace scene.

The course is worth 1 credit. Assessment is in the form of a five-scale report, awarded on the basis of a test identical to the knowledge survey, written at the beginning of October. The grading is based on the percentiles of student results as follows:

  • lowest 20%: failed (1)
  • 20–40%: passed (2)
  • 40–60%: accepted (3)
  • 60–80%: good (4)
  • best 20%: excellent (5)

SYLLABUS

  1. Mathematical foundations. Normal form of numbers. The SI system of units: base units and prefixes. The use of symbols. Angles. Functions: linear functions, powers, exponential, logarithmic and trigonometric functions. Derivative and integral. Geometry: circumference, area, surface area and volume. (3 periods)
  2. Kinematics and dynamics. Vectors. Kinematics: uniform motion and circular motion. Dynamics: interactions, Newton’s laws, inertial systems, types of forces. (3 periods)
  3. Energy. Work. Kinetic energy. Potential energy: gravitational, elastic. Mechanical energy and its conservation. Power. (1.5 periods)
  4. Hydrostatics. Density. Pressure. Hydrostatic pressure (0.5 periods)
  5. Oscillations. Fundamental concepts: amplitude, period, frequency, angular frequency. Harmonic oscillations. Damped oscillations. Natural angular frequency. Driven oscillations and resonance. (2 periods)
  6. Waves. Fundamental concepts: wavelength, (angular) wave number, speed of propagation. Types of waves: longitudinal and transverse. Wave propagation: reflection and refraction (Snell’s law). Interference, standing waves. Diffraction. Linear polarisation. Fundamentals of acoustics. (2 periods)
  7. Electricity. Stationary charges, electrostatics: Coulomb’s law, electric field, electric field lines. Electric potential and voltage. Dipole. Accumulating charges: capacitance, capacitors in series and in parallel. Moving charges, electric current: Ohm’s law, resistance and conductance, resistors in series and in parallel, Kirchhoff’s laws. Electric power. Direct current and alternating current, capacitors in alternating current circuits. (2 periods)
  8. Magnetism. Magnetic field and magnetic field vector. Interaction between moving charges (currents) and the magnetic field (Lorentz force). Magnetic properties of matter: permanent magnets, ferro-, para- and diamagnetic substances. Magnetic moment, intrinsic magnetic moment of charged particles (electron and proton spin). Magnetic effects of currents. Electromagnetic induction: magnetic flux, Faraday’s law, Lenz’s law. Electric motor and electric generator. Self-inductance, inductors in an alternating current circuit. (2 periods)

RECOMMENDED READING

  • course handouts
  • lecture notes

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